Focused on solving unmet needs in ophthalmology

 

Addressing significant unmet medical needs for better topical therapy
 
Product candidate
Investigational indication(s)
Formulation
Phase I
Phase II
Phase III
Clinical Stage
OCS-01
DIABETIC MACULAR EDEMA
 
OCS-01
INFLAMMATION AND PAIN FOLLOWING OCULAR SURGERY
 
OCS-02
UVEITIS
 
OCS-02
DRY EYE
Pre-Clinical Stage
MULTIPLE CANDIDATES
RETINAL DISORDERS
 
MULTIPLE CANDIDATES
OCULAR INFLAMMATION

OCS-01 is based on SNP technology while OCS-02 is based on single chain antibody fragment (scFv) against TNFα

OCS-01: A potential paradigm shift in DME treatment

Our most advanced product candidate, OCS-01, is in clinical trials in patients with DME and in planning phase for potential front-of-the-eye indications.

OCS-01 has been developed from Oculis’ solubilizing nanoparticle (SNP) technology, a proprietary platform that enables the formulation of drugs as non-invasive topical treatments and enhances their bioavailability in the relevant eye tissues. If approved in DME, it has the potential to provide a new option for patients.

OCS-01: A potential treatment for Post-cataract Surgery Inflammation

Because patients undergoing cataract surgery are usually on several medications daily, adding more eye drops can be challenging. A long-acting topical solution such as OCS-01 has the potential of reducing the frequency of the burden of administration to patients.

OCS-02: THE POTENTIAL OF topical anti-TNF alpha therapy for ophthalmic indications

The compound, named OCS-02, is based on a proprietary single-chain antibody fragment technology specifically designed for topical delivery. Efficacy and safety were evaluated in three clinical trials including two controlled studies under IND. The studies demonstrated a promising profile for treating inflammatory conditions of the anterior segment of the eye including Uveitis and Dry Eye Disease.